RNA-proteome correlation - all-proteome

This report summarizes the correlation analysis between RNA and proteome expression. Correlations are calculated per gene (across samples) and per sample (across genes) using Pearson’s correlation coefficient.

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Gene-wise correlations

The histogram shows all gene-wise correlations (blue) across 77 samples. Significant correlations (FDR adjusted p-values < 0.05) are depicted in red. You can enable/disable layers of the histogram by clicking on the respective legend. The dashed line depicts the median correlation based on all genes.

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Summary table

No. of correlations	all	negative	positive	median cor.
all	9067	508	8559	0.4222783
FDR 5%	6615	17	6598	0.5137157

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Correlation-rank-plot

Genes are ranked according to their RNA / proteome correlation (x-axis) and plotted against the actual correlation value (y-axis). Gene names can be inferred by hovering over the data points.

Top 10 correlated genes

Left: positive correlation; right: negative correlation

geneSymbol correlation p.value p.value.fdr HEBP1 0.8855878 0 0e+00 UBE2Z 0.8846048 0 0e+00 SLC9A3R1 0.8738768 0 0e+00 NFIX 0.8728659 0 0e+00 PREP 0.8721588 0 0e+00 PPME1 0.8717970 0 0e+00 STARD10 0.8705218 0 0e+00 COCH 0.8703937 0 0e+00 AMDHD1 0.8674652 0 2e-07 GSTM3 0.8641978 0 0e+00

geneSymbol correlation p.value p.value.fdr ICA1L -0.4923726 0.0006863 0.0012719 PTPRD -0.4789702 0.0000105 0.0000265 DNAH1 -0.4384674 0.0106984 0.0161053 EFCAB6 -0.4089148 0.0223672 0.0319426 GNPDA1 -0.3951992 0.0003750 0.0007241 SEC14L3 -0.3496267 0.0018284 0.0031291 GRM5 -0.3409612 0.0817820 0.1056142 FGFR3 -0.3203342 0.0064606 0.0100632 GPRIN1 -0.3081318 0.0598247 0.0789794 ZNF106 -0.3074925 0.0178328 0.0258415

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Sample-wise correlations

For each of the 77 samples Pearson correlations between RNA / proteome across all genes were calculated and are depicted as bubble chart. The size of each bubble scales with correlation value.

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Created on 2020-11-12 20:28:30

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