RNA-proteome correlation - all-proteome

This report summarizes the correlation analysis between RNA and proteome expression. Correlations are calculated per gene (across samples) and per sample (across genes) using Pearson’s correlation coefficient.


Gene-wise correlations

The histogram shows all gene-wise correlations (blue) across 77 samples. Significant correlations (FDR adjusted p-values < 0.05) are depicted in red. You can enable/disable layers of the histogram by clicking on the respective legend. The dashed line depicts the median correlation based on all genes.


Summary table

No. of correlations all negative positive median cor.
all 9067 508 8559 0.4222783
FDR 5% 6615 17 6598 0.5137157

Correlation-rank-plot

Genes are ranked according to their RNA / proteome correlation (x-axis) and plotted against the actual correlation value (y-axis). Gene names can be inferred by hovering over the data points.

Top 10 correlated genes

Left: positive correlation; right: negative correlation
geneSymbol correlation p.value p.value.fdr
HEBP1 0.8855878 0 0e+00
UBE2Z 0.8846048 0 0e+00
SLC9A3R1 0.8738768 0 0e+00
NFIX 0.8728659 0 0e+00
PREP 0.8721588 0 0e+00
PPME1 0.8717970 0 0e+00
STARD10 0.8705218 0 0e+00
COCH 0.8703937 0 0e+00
AMDHD1 0.8674652 0 2e-07
GSTM3 0.8641978 0 0e+00
geneSymbol correlation p.value p.value.fdr
ICA1L -0.4923726 0.0006863 0.0012719
PTPRD -0.4789702 0.0000105 0.0000265
DNAH1 -0.4384674 0.0106984 0.0161053
EFCAB6 -0.4089148 0.0223672 0.0319426
GNPDA1 -0.3951992 0.0003750 0.0007241
SEC14L3 -0.3496267 0.0018284 0.0031291
GRM5 -0.3409612 0.0817820 0.1056142
FGFR3 -0.3203342 0.0064606 0.0100632
GPRIN1 -0.3081318 0.0598247 0.0789794
ZNF106 -0.3074925 0.0178328 0.0258415

Sample-wise correlations

For each of the 77 samples Pearson correlations between RNA / proteome across all genes were calculated and are depicted as bubble chart. The size of each bubble scales with correlation value.



Created on 2020-11-12 20:28:30